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MCQs 1:

What facilitates the specific binding of HIV to the CD4 surface molecules on the host membrane?





Topic: HIV Binding Mechanism

Correct Answer: A) gp 120

Detailed Hint:
  • The binding of HIV to the host's CD4 surface molecules is a specific process and is facilitated by certain proteins.
  • Among the options provided, it's gp 120 that plays a key role in this binding process.
  • Thus, the correct answer is A, "gp 120".

MCQs 2:

Into how many distinct stages can the life cycle of HIV be divided?





Topic: Stages of HIV Life Cycle

Correct Answer: D) 6 stages

Detailed Hint:
  • HIV, the human immunodeficiency virus, goes through a specific sequence of stages during its life cycle.
  • This sequence includes distinct processes such as binding and fusion, reverse transcription, integration, transcription and translation, assembly, and finally, budding and maturation.
  • Given this, the correct answer is D — there are 6 stages in the HIV life cycle.

MCQs 3:

The therapeutic approach known as HAART is primarily used to treat which disease?





Topic: Therapeutic Approaches in Disease Management

Correct Answer: C) AIDS

Detailed Hint:
  • HAART, standing for Highly Active Anti-Retroviral Therapy, is a combination of medications used in the management of a specific disease.
  • This approach combines three or more anti-HIV medications in a single regimen, sometimes referred to as a cocktail.
  • The primary disease treated by HAART is HIV, which leads to AIDS.
  • Therefore, the correct answer is C — AIDS.

MCQs 4:

People suffering from which disease are most likely to be susceptible to numerous opportunistic diseases?





Topic: Disease Susceptibility

Correct Answer: D) AIDS

Detailed Hint:
  • An individual's susceptibility to opportunistic diseases often increases when their immune system is significantly compromised.
  • Among the diseases listed, AIDS, or Acquired Immunodeficiency Syndrome, is widely known to heavily compromise the immune system.
  • This leaves individuals with AIDS particularly vulnerable to a broad range of opportunistic diseases.
  • Thus, the correct answer is D — AIDS.

MCQs 5:

Which component is responsible for binding the virus to cells that have sialic acid on their membranes?





Topic: Viral Attachment Mechanisms

Correct Answer: A) Hemagglutinin (HA)

Detailed Hint:
  • The process of viral attachment to host cells is facilitated by specific components present on the surface of the virus.
  • In this context, Hemagglutinin (HA) plays a crucial role in binding the virus to cells that feature sialic acid on their membranes.
  • Therefore, the correct answer is A — Hemagglutinin (HA).

MCQs 6:

What is the term for viruses that target the immune system, use RNA as their genetic material, reproduce slowly, and have a long incubation period?





Topic: Viral Classification

Correct Answer: B) Lentiviruses

Detailed Hint:
  • Viruses can be classified based on several characteristics, including their target cells, genetic material, replication speed, and incubation period.
  • Lentiviruses, a subgroup of retroviruses, are characterized by their RNA genetic material, slow replication process, and long incubation periods.
  • Hence, the correct answer is B — Lentiviruses.

MCQs 7:

Which aspect is the genome of the influenza virus associated with?





Topic: Influenza Virus Structure

Correct Answer: B) 5 viral proteins

Detailed Hint:
  • The structure of a virus, including its genome, is associated with specific components that facilitate its ability to infect and replicate within host cells.
  • In the case of the influenza virus, its genome is associated with 5 types of proteins.
  • Therefore, the correct answer is B — 5 viral proteins.

Question 8:

What is the shape of the Poliovirus?





Topic: Viral Structure

Correct Answer: D) Golf ball shape

Detailed Hint:
  • The structure of viruses can vary significantly, with shapes ranging from helical to complex.
  • Poliovirus, a member of the Enterovirus genus, is known for its specific form.
  • It is characterized by a spherical shape, similar to a golf ball.
  • Thus, the correct answer is D — Golf ball shape.

Question 9:

What is the calculated replication time of some viruses, and within what time frame can they destroy a host cell?





Topic: Viral Replication

Correct Answer: B) 70 seconds, 10 minutes

Detailed Hint:
  • The replication time of viruses can vary widely, and the speed of this process contributes significantly to their ability to cause disease.
  • It's been calculated that some viruses can replicate themselves within just 70 seconds.
  • Furthermore, in as little as 10 minutes, these viruses can destroy a host cell after making hundreds of copies of themselves.
  • Therefore, the correct answer is B — 70 seconds, 10 minutes.

Question 10:

What type of RNA does the influenza virus possess?





Topic: Viral Genetic Material

Correct Answer: C) Single-stranded segmented RNA

Detailed Hint:
  • The genetic material of viruses can be either RNA or DNA, and it can be single- or double-stranded.
  • Influenza viruses are a type of RNA virus.
  • Specifically, they carry single-stranded RNA that is segmented into separate RNA pieces.
  • Hence, the correct answer is C — Single-stranded segmented RNA.

Question 11:

What type of genetic material and protein coat does HIV possess?





Topic: HIV Structure

Correct Answer: B) Single-stranded RNA (ssRNA)

Detailed Hint:
  • HIV, the Human Immunodeficiency Virus, is known for its unique structure, which aids its ability to invade host cells.
  • It possesses a protein coat and genetic material.
  • Specifically, its genetic material is single-stranded RNA (ssRNA).
  • Therefore, the correct answer is B — Single-stranded RNA (ssRNA).

Question 12:

Which of the following is not a criterion used to classify viruses?





Topic: Viral Classification

Correct Answer: A) Type of reproduction

Detailed Hint:
  • Viruses are classified based on several factors, including their nucleic acid type, presence or absence of an envelope, and size and shape.
  • However, the type of reproduction is not among the standard criteria used for viral classification.
  • Thus, the correct answer is A — Type of reproduction.

Question 13:

What is the term for an RNA virus that has a DNA stage in its life cycle?





Topic: Viral Life Cycles

Correct Answer: D) Retrovirus

Detailed Hint:
  • Viruses follow diverse life cycles, with some RNA viruses undergoing a DNA stage.
  • These viruses are specifically known as retroviruses.
  • Therefore, the correct answer is D — Retrovirus.

Question 14:

What are the two major protein components that make up the spikes in HIV?





Topic: HIV Structure

Correct Answer: A) gp-120 and gp-41

Detailed Hint:
  • HIV, the Human Immunodeficiency Virus, has a unique structure that includes spikes made up of protein components.
  • These include two major proteins: gp-120 and gp-41.
  • The spike's head comprises gp120, and its tail is made of gp41.
  • Therefore, the correct answer is A — gp-120 and gp-41.

Question 15:

What do the proteins on a virus's surface use to recognize its target on the host cell's surface?





Topic: Viral Recognition Mechanism

Correct Answer: A) Proteins or sugars

Detailed Hint:
  • Viruses use specific methods to recognize and attach to host cells.
  • Proteins on the virus's surface play a crucial role in recognizing targets on a host cell's surface.
  • These targets are usually proteins or sugars.
  • Hence, the correct answer is A — Proteins or sugars.

Question 16:

What is accurate about the envelope of a virus?





Topic: Viral Envelope Characteristics

Correct Answer: D) All of the above

Detailed Hint:
  • The envelope of a virus carries several defining attributes, contributing to its ability to infect host cells.
  • It is typically derived from the host cell membrane and is lipoprotein in nature.
  • Moreover, it features projecting spikes on the surface.
  • Therefore, the correct answer is D — All of the above.

Question 17:

What is the comparative diameter ratio between E.coli and HIV?





Topic: Comparative Sizes of Microorganisms

Correct Answer: B) One twentieth

Detailed Hint:
  • Comparing the diameters of various pathogens provides insight into their relative sizes.
  • The diameter of the HIV particle is significantly smaller than that of E.coli.
  • It is approximately one twentieth of the length of an E.coli bacterium, highlighting its microscopic size.
  • Therefore, the correct answer is B — One twentieth.

Question 18:

Which geometric shape commonly describes the capsid shape of viruses?






Topic: Viral Capsid Shapes

Correct Answer: C) Icosahedron

Detailed Hint:
  • Viral capsids come in various geometric shapes, which contribute to their unique structural characteristics.
  • One of the most common shapes for a viral capsid is an icosahedron.
  • This structure provides stability and efficiency for the virus.
  • Therefore, the correct answer is C — Icosahedron.

Question 19:

Which enzyme is not encoded by the pol gene in viruses?





Topic: Viral Genes and Enzymes

Correct Answer: D) RNA polymerase

Detailed Hint:
  • The pol gene in viruses encodes several crucial enzymes that facilitate the viral replication process.
  • However, not all enzymes involved in virus replication are encoded by the pol gene.
  • Specifically, the pol gene does not encode for RNA polymerase.
  • Hence, the correct answer is D — RNA polymerase.

Question 20:

In a bacteriophage, which structure is more intricate than the others?





Topic: Bacteriophage Structure Complexity

Correct Answer: C) Head

Detailed Hint:
  • Bacteriophages, viruses that infect bacteria, have distinct structural components.
  • Each of these parts - the body, tail, and head - has a unique structure and complexity.
  • While each part is essential, the head of a bacteriophage is often more intricate than the other parts.
  • Hence, the correct answer is C — Head.

Question 21:

What is the term for the outer protein covering present in viruses?





Topic: Viral Covering

Correct Answer: A) Capsid

Detailed Hint:
  • Viruses are composed of several layers that serve various functions.
  • The outermost layer, often made of protein, plays a significant role in protecting the virus and facilitating its attachment to host cells.
  • This outer protein layer is referred to as the capsid.
  • Thus, the correct answer is A — Capsid.

Question 22:

What type of viruses are bacteriophages?





Topic: Bacteriophage Classification

Correct Answer: A) Double-stranded DNA

Detailed Hint:
  • Bacteriophages are a category of viruses that have a specific target: bacteria.
  • They are categorized based on their type of genetic material.
  • Bacteriophages are typically double-stranded DNA viruses.
  • Therefore, the correct answer is A — Double-stranded DNA.

Question 23:

Which of the following viruses is characterized by a spherical shape?





Topic: Virus Morphology

Correct Answer: B) Polio

Detailed Hint:
  • Viruses come in a variety of shapes, each unique to its type.
  • While many viruses are complex in shape, some, like the Polio virus, are spherical.
  • This sphere-like morphology is distinct to the Polio virus among the options provided.
  • Therefore, the correct answer is B — Polio.

Question 24:

The configuration of neuraminidase or sialidase can be best described as which of the following?





Topic: Enzyme Structures

Correct Answer: A) Mushroom shape

Detailed Hint:
  • Enzymes in viruses exhibit various forms, impacting their function and interaction with host cells.
  • Neuraminidase or sialidase, an enzyme in certain viruses, has a unique mushroom shape.
  • This shape allows it to interact effectively with other molecules.
  • Thus, the correct answer is A — Mushroom shape.

Question 25:

Which treatment approach is considered most effective for HIV infection?





Topic: HIV Treatment

Correct Answer: D) Highly active antiretroviral therapy

Detailed Hint:
  • Several strategies are employed in the treatment of HIV, aiming to control virus replication and halt disease progression.
  • Highly active antiretroviral therapy (HAART) combines three or more anti-HIV medications in a daily regimen, sometimes referred to as a "cocktail".
  • HAART has proved to be the most effective treatment strategy for HIV.
  • Hence, the correct answer is D — Highly active antiretroviral therapy.

Question 26:

Why are phage viruses typically abundant in the intestines of humans and animals?





Topic: Phage Viruses Habitat

Correct Answer: A) Abundant bacteria are present

Detailed Hint:
  • Phage viruses have a specific habitat preference based on their target host and environmental conditions.
  • In the case of human and animal intestines, the environment is rich with their primary targets, bacteria.
  • While water and nutrients are also abundant in the intestines, it is the high concentration of bacteria that primarily attracts phage viruses.
  • Therefore, the correct answer is A — Abundant bacteria are present.